Following the exploits of the two famous droids from the Star Wars movies, this animated series takes place before Episode IV: A New Hope, and detailed the adventures of the two as they were passed on from different masters. Between freeing the helpless, fleeing bounty hunters (including assassin droid IG-88), pirates, escaping AWOL droids and surviving tight situations with diplomacy, the series never featured any other Star Wars characters except for Boba Fett, making a cameo in episode #14, "The Great Heep," which was shown as a two-part television special on the night of June 7, 1986.

As in the movies, C3PO was voiced by Anthony Daniels. Additionally, all of the classic droid and blaster sounds were present. This short series lasted only one season.

The series appeared alongside episodes of "Ewoks" in 1986 as "The Droids and Ewoks Adventure Hour."

20th Century Fox released various episodes of "Droids" on DVD in 2004.